The year was 2008. The second wave of therapeutic biological products was just around the corner. By now it was known that many of these products were susceptible to oxidative damage by residual hydrogen peroxide left over after aeration of the aseptic processing equipment and barrier system. How sensitive these products were to low concentrations of residual hydrogen peroxide was difficult to assess because there were no obvious measurement systems capable of quickly, accurately and precisely measuring vapor phase hydrogen peroxide below a few hundred parts per billion (ppb).
March 18, 2020
The most effective and valuable new therapeutic products today are biologics, including peptides, proteins, and antibody-drug conjugates (ADCs), as well as cells, cell-derived products, and gene therapies. Many of these products are susceptible to oxidative damage by trace levels of hydrogen peroxide.
March 11, 2020